Acute myeloid leukemia (AML) is a heterogeneous disease characterized by malignant proliferation of myeloid hematopoietic stem/progenitor cells.NPM1 represents the most frequently mutated gene in AML and approximately 30% of AML cases carry NPM1 mutations.Mutated NPM1 result in the cytoplasmic localization of NPM1 (NPM1c).NPM1c interacts with other
Occupational Violence and Staff Safety in Health-Care: A Cross-Sectional Study in a Large Public Hospital
Zainab R Al-Shaban,1 Sultan T Al-Otaibi,2 Hatem A Alqahtani3 1Primary Healthcare Centers, Department of Occupational Medicine, Ministry of Health, Qatif, Kingdom of Saudi Arabia; 2Department of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Mattress Protector Dammam, Kingdom of Saudi Arabia; 3Department of Family a
Genome-wide association analysis reveal the genetic reasons affect melanin spot accumulation in beak skin of ducks
Abstract Background Skin pigmentation Vanity Mirror is a broadly appearing phenomenon of most animals and humans in nature.Here we used a bird model to investigate why melanin spot deposits on the skin.Results Our result showed that growth age and the sunlight might induce melanin deposition in bird beak skin which was determined by genetic factors